Inhibition of EZH2 alleviates SAHA-induced senescence-associated secretion phenotype in small cell lung cancer cells

Abstract Chemotherapy has been widely used in small cell lung cancer (SCLC) treatment folding saw in the past decades.However, SCLC is easy to recur after chemotherapy.The senescence of cancer cells during chemotherapy is one of the effective therapeutic strategies to inhibit the progression of cancer.Nevertheless, the senescence-associated secreti

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Kidney Disease Profiles Among Adolescents In Indonesia

Background: Each kidney injury may develop into chronic kidney disease (CKD) and end stage renal disease (ESRD) that associates with high mortality and socio-economic burden.There is limited data about clinical characteristics of children having CKD in developing countries, espesially in Indonesia.Objective: To describe clinical profiles and charac

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